2 what is the difference between purines and pyrimidines

The purines and pyrimidines both consist of heterocyclic rings. Together, the two sets of compounds make up the nitrogenous bases. Yet, there are distinct differences between the molecules. Obviously, because purines consist of two rings rather than one, they have a higher molecular weight. The ring structure also affects the melting points and solubility of the purified compounds.

The human body synthesizes anabolism and breaks down catabolism the molecules differently. The end product of purine catabolism is uric acid, while the end products of pyrimidine catabolism are ammonia and carbon dioxide. The body does not make the two molecules in the same location, either. Purines are synthesized primarily in the liver, while a variety of tissues make pyrimidines. Here is a summary of the essential facts about purines and pyrimidines:.

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Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. The difference between purine and pyrimidine are the following -.

Purines are bigger in size. Pyrimidines are smaller in size. Purines have one pentose and one hexose ring. Pyrimidines have one hexo-cyclic ring. Chemical formula. Chemical formula of purine — C 5 H 4 N 4. Chemical formula of pyrimidine — C 4 H 4 N 2. Purines are soluble in water. Pyrimidines are insoluble in water. Catabolic end product. Purine catabolic end product — uric acid. Pyrimidine catabolic end product — carbon dioxide, beta-amino acids and ammonia.

Melting point. Molecular mass. Molecular mass of purine — Molecular mass of pyrimidine — The pyrimidines that are synthesized from the nucleic acids, with the help of nucleotidases and the pyrimidine nucleoside phosphorylase, form the four-amino group of cytosine and five-methylcytosine.

It releases ammonia and carbon dioxide. Since the purines and pyrimidines are heterocyclic, they can come together to form several nitrogenous bases. However, since purines are made up of two rings instead of one, they have a heavier molecular weight than that of others. The circular ring structure plays its role in the melting points and solubility of these compounds.

The aforementioned ways represent how these molecules are synthesized and broken down differently by the body in different places, as the purines are manufactured in the liver and the pyrimidines in the tissues. Double carbon-nitrogen ring with 4 Nitrogen atoms. Single carbon-nitrogen ring with two nitrogen atoms.

Larger in size. Smaller to Purines. Melting Point. Molar Mass. Adenine and Guanine. Solubility in Water. It occurs in the liver.